… protected against neuronal loss and improved motor function in an in vivo 6-OHDA model of
Parkinson’s disease (PD)… to protect dopamine neurons from degeneration in a model of PD. …

… of GK for protecting TH + neurons by multiple and … neurons in the MPTP mouse model
of PD, and is the vital player in the development and neurogenesis of dopaminergic neurons (…

… Here, the cellular and molecular aspects as well as the therapeutical options for rejuvenating
glia-neuron dialogue will be discussed together with major glial-derived mechanisms and …

… AD and PD mouse models and 2) regenerative medicine in AD and PD mouse models, and
… and can protect neurons from Aβ species, uncoupling tau protein, and oxidative stress [131]. …

… The model has rejuvenated PD research and opened new frontiers in the quest for more
novel therapeutic and adjuvant agents for PD. Hence, this review summarizes the role of MPTP …

… The recent introduction of a rodent model exhibiting an age-… (Bottom) Neuronal “rejuvenation”
strategies aimed at … , halt, or delay neuronal dysfunction and degeneration linked to both …

… As expected, these data supported the notion that HS could protect loss … mice model, we
performed further investigations using MPP + -induced DAergic-like neurons as a cellular model …

… The dopaminergic neurodegeneration in the substantia nigrapars compacta (SNpc) and
striatum of the midbrain is the important pathological feature of Parkinson's disease (PD). It has …

… However, rodent models may not sufficiently represent the … These results suggest that the
CTN potentially protects cells … pathogenesis, although they are known to remain rejuvenated …

… impaired neurogenic niches to rejuvenate and repair the aged … in aging mice and to protect
nigrostriatal DAergic neurons in … Of specific interest, in MPTP-aged mouse model of PD we …